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Activity Details

Free CME
1 AMA PRA Category 1 Credit(s)
Released: June 18, 2020
Expires: April 18, 2021
60 minutes to complete

Accredited By

The University of Nebraska Medical Center, Center for Continuing Education

Target Audience

The target audience for this activity is community and academic medical oncologists, hematologists, advanced practitioners (NP/PA/PharmD), and other clinicians who treat patients with lymphoma/myeloma/leukemia.

Learning Objectives

After participating in this activity, participants should be better able to:

  • Review the structure and function of CAR T-cells and the mechanism of action in patients with hematologic malignancies
  • Review clinical trial data of CAR T-cell–based therapies for the treatment of patients with lymphoma, and describe where CAR T-cell therapies might fit into the treatment landscape
  • Evaluate emerging clinical data and novel approaches to CAR T-cell therapy for patients with myeloma
  • Identify characteristics of patients with acute lymphoblastic leukemia who are appropriate for treatment with CAR T-cell therapy
  • Develop strategies to mitigate adverse events that may be encountered with the use of CAR T-cell therapy

Activity Description

This activity is designed to evaluate emerging CAR T data and discuss the challenges of managing CAR T specific adverse events to aid community clinicians who treat patients with lymphoma, myeloma, and leukemia.

Statement of Educational Need

Given the recent approval of various CAR T-cell–based therapies for the treatment of patients with hematologic malignancies, as well as the associated volume of emerging data of both currently approved and emerging CAR T-cell therapies, it is critical that oncologists be able to evaluate the benefits of these agents, select appropriate patients for therapy or clinical trials, and prevent and manage adverse events.

Faculty

Julie Vose, MD, MBA
Chief
Neumann M. and Mildred E. Harris Professorial Chair
Division of Oncology & Hematology
University of Nebraska Medical Center
Omaha, Nebraska

Disclosures
Consulting Fees: AbbVie, Acerta/AstraZeneca, BeiGene, Epizyme, Janssen/Pharmacyclic, Karyopharm, Kite Pharma, Legend Pharmaceuticals, Nordic Nanovector, Novartis, Roche, Sandoz, Vaniam Group, Verastem

Grants/Research Support: Acerta Pharma, Amgen, AstraZeneca, Bristol-Myers Squibb, Celgene Corporation, Incyte Corporation, Kite Pharma, Merck, Novartis, Seattle Genetics


Conflict of Interest Policy/Disclosure Statement

Faculty and Planning Committee Disclosures

As a provider accredited by ACCME, the UNMC Center for Continuing Education must ensure balance, objectivity, independence, and scientific rigor in its educational activities. Presenters are encouraged to provide a balanced view of therapeutic options by utilizing either generic names or the trade names of several to ensure impartiality.

All presenters, planners, and others in a position to control continuing medical education content participating in a UNMC Center for Continuing Education activity are required to disclose relationships with commercial interests. A commercial interest is any entity producing, marketing, reselling, or distributing health care goods or services consumed by, or used on, patients. Disclosure of these commitments and/or relationships is included in activity materials so that participants in the activity may formulate their own judgments in interpreting its content and evaluating its recommendations.

This activity may include presentations in which presenters may discuss off-label and/or investigational use of pharmaceuticals or instruments not yet FDA-approved. Participants should note that the use of products outside currently FDA-approved labeling should be considered experimental and are advised to consult current prescribing information for FDA-approved indications.

All materials are included with the permission of the authors. The opinions expressed are those of the authors and are not to be construed as those of the UNMC Center for Continuing Education or Bio Ascend. The information presented in this activity is not meant to serve as a guideline for patient management; primary references, relevant practice guidelines, and full prescribing information should be consulted.

The faculty and planning committee members for this activity have no conflicts to disclose with the exception of those listed on the following presenter slide. All disclosed conflicts of interest have been resolved by independent content review.

Accreditation Statement

Continuing Education

The University of Nebraska Medical Center (UNMC) Center for Continuing Education is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians. 

The UNMC Center for Continuing Education designates this enduring activity for a maximum of 1 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity. 

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the ACCME through the joint providership of the UNMC Center for Continuing Education and Bio Ascend.

Instructions for Receiving Credit

There are no fees for participating and receiving credit for this activity. During the accredited period, participants must 1) read the learning objectives and faculty disclosures; 2) study the educational activity; 3) complete the pre- and post-activity assessments and evaluation.

Participants who complete the educational activity, pre- and post-activity assessments, and evaluation will receive a certificate of credit.

Materials will be available online through April 18, 2021.

Statement of Commercial Support

This activity is supported by independent educational grants from Celgene Corporation and Gilead Sciences, Inc.

Disclaimer Statement/Disclosure of Unlabeled Use

UNMC CCE and Bio Ascend do not recommend the use of any agent outside of the labeled indication. The opinions expressed in the educational activity do not necessarily represent the views of UNMC CCE and Bio Ascend.

Contact Information for Questions About the Activity

cme@bioascend.com

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