Sagar Lonial, MD
Sagar Lonial, MD
Professor and Vice Chair of Clinical Affairs
Department of Hematology and Medical Oncology
Winship Cancer Institute
Emory University School of Medicine
Atlanta, GA


Joseph Mikhael, MD, MEd, FRCPC, FACP
Joseph Mikhael, MD, MEd, FRCPC, FACP
Associate Dean, Mayo School of Graduate Medical Education
Deputy Director - Education, Mayo Clinic Cancer Center
Associate Professor, Mayo College of Medicine
Scottsdale, AZ

Activity Details

Release Date: April 9, 2014
Expiration Date: April 9, 2015
Credit Types: CME
Credit Amount: 1.0 AMA PRA Category 1 Credit™
Estimated Time to Complete Activity 1.0 hours
Cost There are no fees for participating in or receiving credit for this activity.

Accredited by

Physicians’ Education Resource®, LLC
Physicians’ Education Resource®, LLC


Click here for additional educational resources for this activity.

Activity Description

The Clinical Case Discussions series is an online activity designed to allow participants to hear thought leaders discuss their treatment approaches, decision points, and real-life challenges in treating patients with cancer.

This activity will focus on multiple myeloma and will follow the treatment cycle of two patients diagnosed with relapsed/refractory multiple myeloma.


Topics for Discussion:

  • 56-year-old transplant-eligible patient with multiple myeloma, initially treated with bortezomib, lenalidomide, and dexamethasone (RVD), but no maintenance
  • 61-year-old transplant-eligible patient with multiple myeloma, initially treated with cyclophosphamide, bortezomib, and dexamethasone (CyBorD), and lenalidomide maintenance

Learning Objectives

At the conclusion of this activity, participants should be better prepared to:

  • Assess how new data can be incorporated into individualized treatment plans for patients, based upon an evaluation of efficacy and safety, as well as patient characteristics, such as age and performance status
  • Incorporate next-generation therapeutics into individualized treatment plans

Target Audience

This online activity is directed toward medical oncologists/hematologists and fellows who treat patients with multiple myeloma.

Requirements for Successful Completion

In order to receive a CME certificate, participants must read Clinical Case Discussions: Treating Relapsed/Refractory Multiple Myeloma, listen to the audio, complete the post-test with a passing score of 70% or higher, and complete the evaluation and request for credit. Participants may immediately download a CME certificate upon completion of these steps.



Conflict of Interest Policy/Disclosure Statement

The following individuals have relevant financial relationships with commercial interests to disclose:

Sagar Lonial, MDConsultant: Millennium Pharmaceuticals, Celgene, Novartis, Bristol-Myers Squibb, Onyx Pharmaceuticals, sanofi-aventis

Joseph Mikhael, MD, MEd, FRCPC, FACP Grant/Research Support: Onyx Pharmaceuticals, sanofi-aventis, Celgene

The following individuals have no relevant financial relationships with commercial interests to disclose: Physicians’ Education Resource®, LLC, Planning Staff – Dru Dace, PhD, Francie Jallad, and David Lee, PhD

Accreditation Statement for Physicians

Physicians’ Education Resource®, LLC is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Designation of Credit

Physicians’ Education Resource®, LLC designates this enduring material for a maximum of
1.0 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Statement of Commercial Support

This activity is supported by an educational grant from Onyx Pharmaceuticals.

Disclaimer Statement

The opinions expressed in the content are solely those of the individual faculty members and do not reflect those of Physicians’ Education Resource®, LLC, or the company that provided commercial support for this CME activity.

Disclosure of Unlabeled Use

This CME activity may contain discussions about off-label/unapproved uses of drugs. For additional information about approved uses, including approved indications, contraindications, and warnings, participants are advised to consult prescribing information for all products discussed or consult the Physicians’ Desk Reference. The information provided in this CME activity is for continuing medical education purposes only and is not meant to substitute for the independent medical judgment of a physician relative to diagnostic and treatment options for a specific patient’s medical condition.

Contact Information for Questions About the Activity

Physicians’ Education Resource®, LLC
666 Plainsboro Road, Suite 356
Plainsboro, NJ 08536
Phone: (888) 949-0045

Hardware / Software Requirements

OpenCME recommends using the latest versions of these supported browsers: Google Chrome, Mozilla Firefox, Safari; and Microsoft Internet Explorer versions 8, 9, or 10. Depending on your browser of choice, additional software, such as Adobe Reader® and Adobe® Flash® Player may be required.

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