Provider Statement

This continuing medical education activity is provided by

This continuing nursing education activity is provided by

Support Statement

This activity is supported by educational grants from Genentech, Inc., Genzyme, a Sanofi Company, and Novartis Pharmaceuticals Corporation.

There is no non-commercial support for this activity.

Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.

Activity Chair

Patricia K. Coyle, MD, FAAN, FANA
Professor and Vice Chair (Clinical Affairs)
Department of Neurology
Multiple Sclerosis Comprehensive Care Center
Stony Brook University Medical Center
Stony Brook, NY

Consulting Fees: Accordant, Bayer, Biogen, Genentech/Roche, Mallincrkrodt, Novartis, Sanofi-Genzyme, Serono
Contracted Research: Actelion, Genentech/Roche, Novartis, Opexa

Steering Committee

Guy J. Buckle, MD, MPH
Director of Neuroimaging Research
Andrew C. Carlos MS Institute at Shepherd Center
Atlanta, GA

Consulting Fee: Bayer, Biogen, EMD-Serono, Genentech, Genzyme-Sanofi, Mallinckrodt, Novartis, Teva
Speakers Bureau: Biogen, EMD-Serono, Genentech, Genzyme-Sanofi, Mallinckrodt, Novartis, Teva
Contracted Research: Biogen (PI)

Bruce A. Cohen, MD
Professor of Neurology
Northwestern University
Feinberg School of Medicine
Northwestern Comprehensive Multiple Sclerosis Program
Chicago, IL

Consulting Fee: Biogen-Idec, EMD-Serono, Genentech, Genzyme, Novartis

Clyde E. Markowitz, MD*
Associate Professor of Neurology
Director, Multiple Sclerosis Center
Hospital of the University of Pennsylvania
Perelman School of Medicine
Philadelphia, PA

Consulting Fee: Bayer, Biogen, EMD-Serono, Genentech, Genzyme, Novartis, Opexa, Roche, Sanofi, Teva

*Author for this activity.

External Reviewer

Brian M. Shepler, PharmD
Disclosures: No relevant financial relationships to disclose.

Nurse Planners

Barbara A. Niedz, PhD, RN, CPHQ
Disclosures: No relevant financial relationships to disclose.

Amy Perrin Ross, APN, MSN, CNRN, MSCN
Consulting Fees: Acorda, Biogen, EMD Serono, Genzyme, Novartis, Teva
Speakers Bureau: Acorda, Bayer, EMD Serono, Genentech, Genzyme, Mallinckrodt, Novartis, Teva

Purdue University and Vindico Medical Education staff report the following relationship(s):
No relevant financial relationships to disclose.

Signed disclosures are on file at Purdue University and Vindico Medical Education, Offices of Medical Affairs and Compliance.


In accordance with the Accreditation Council for Continuing Medical Education and the American Nurses Credentialing Center’s Standards for Commercial Support, all CME/CNE providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, authors, and reviewers involved in the development of CME/CNE content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME/CNE activity content over which the individual has control. Relationship information appears above.

Activity Details

Credit Type: CME/CNE
Credit Amount: 0.25
Release Date: December 30, 2016
Expiration Date: December 30, 2017
Estimated Time to Complete Activity: 15 minutes
Registration Required: No
Fee for Activity: There is no fee for participating in this activity.

Unlabeled and Investigational Usage

The audience is advised that this continuing education activity may contain references to unlabeled uses of FDA-approved products or to products not approved by the FDA for use in the United States. The faculty members have been made aware of their obligation to disclose such usage. All activity participants will be informed if any speakers/authors intend to discuss either non-FDA approved or investigational use of products/devices.


Purdue University is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education, LLC is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Credit Designation

Purdue University designates this enduring material for a maximum of 0.25 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Vindico Medical Education will provide 0.25 contact hours for nurses.

Nurse practitioners can apply for AMA PRA Category 1 Credit(s)™ through the American Academy of Nurse Practitioners (AANP). AANP will accept AMA PRA Category 1 Credit(s)™ from organizations accredited by Accreditation Council for Continuing Medical Education. Nurse practitioners can also apply for credit through their state boards.

American Academy of Physician Assistants (AAPA) accepts certificates of participation for educational activities certified for AMA PRA Category 1 Credit(s)™ from organizations accredited by the ACCME. Physician assistants may receive a maximum of 0.25 hours credit for completing this program.

This enduring material is approved for 1 year from the date of original release, December 30, 2016 to December 30, 2017.

How to Participate in this Activity and Obtain CME/CNE Credit

To participate in this CME/CNE activity, you must read the objectives, answer the pretest questions, read the article, complete the posttest, and fill-in the evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 2 out of 3 of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Purdue University will issue an AMA PRA Category 1 Credit(s)™ Certificate or Vindico Medical Education will issue a Learner-Paced Contact Hours Certificate.


The past several decades have seen tremendous progress in the treatment of relapsing-remitting multiple sclerosis (MS). In contrast, the treatment of progressive MS remains challenging. Improved understanding of the underlying biology of disease progression has led to the identification of therapeutic targets and potential new treatments. This activity will summarize the clinical trial evidence on emerging therapies for progressive MS to help clinicians integrate these agents effectively into future treatment regimens.

Target Audience

The intended audience for this activity is neurologists, neurology nurses, and other health care professionals involved in the treatment of patients with multiple sclerosis.

Purpose/Learning Objectives

Upon successful completion of this CME/CNE activity, participants should be better able to:

  • Compare and contrast the new drug therapy targets and corresponding mechanisms of action of the emerging agents with the current standard therapy for the treatment of multiple sclerosis.
  • Evaluate the latest efficacy and safety data for emerging agents.

Copyright Statement

Created and published by Vindico Medical Education, 6900 Grove Road, Building 100, Thorofare, NJ 08086-9447. Telephone: 856-848-1000; Fax: 856-848-6091. Printed in the USA. Copyright © 2016 Vindico Medical Education All rights reserved. No part of this publication may be reproduced without written permission from the publisher.

The material presented at or in any of Purdue University and Vindico Medical Education continuing education activities does not necessarily reflect the views and opinions of Purdue University and Vindico Medical Education. Neither Purdue University, VIndico Medical Education, the ACCME, the ANCC, nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

CME/CNE Questions?

Contact us at

Suggest a CME Activity

Please provide below the URL and description of an activity you would like to add to OpenCME. You are welcome to add activities as often as you like. To prevent spam or other abuse, activities are reviewed by our editorial team before appearing on OpenCME.

OpenCME for Publishers

Please use the form below if you would like to offer your website visitors high-quality CME content by adding the OpenCME Widget to one or more of your pages.

Start Activity

Select your specialty

You must select a specialty

Send Email to a Colleague

To share this activity with one or more colleagues, enter their e-mail addresses below. To include a personal message, simply overwrite the suggested text below.

(So your recipient knows it's from you.)
Enter multiple recipients separated by a space.
Optionally, replace/modify in the box above the message that will be sent to your colleague(s) with a link to download this app.