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Course Director

George Plitas, MD
George Plitas, MD

Weill Cornell Medical College
Memorial Sloan Kettering Cancer Center
New York, New York

Faculty

Alice Y. Ho
Alice Y. Ho, MD, MBA

Massachusetts General Hospital
Harvard Medical School
Boston, Massachusetts

Heather L. McArthur
Heather L. McArthur, MD, MPH

Samuel Oschin Comprehensive Cancer Institute
Cedars-Sinai Medical Center
Los Angeles, California

Accredited by

Medical Learning Institute, Inc.

View Activity Materials

Activity Description

Immunotherapy has become a new pillar in the treatment arsenal for advanced triple-negative breast cancer (TNBC), and accumulating evidence is supporting its expansion into earlier disease stages as well. To make the most of this therapeutic approach as a component of multimodal management of patients, especially in curative intent settings, it is increasingly important for breast surgeons, medical oncologists, radiation oncologists, pathologists, and other healthcare professionals to collaborate and coordinate the care of patients with TNBC.

This educational on-demand activity based on a recent live web broadcast provides up-to-date information and multidisciplinary perspectives on the current and emerging roles of immune checkpoint inhibitors and combinations throughout the disease continuum of TNBC, as well as practical guidance for optimal integration of these therapies into clinical practice, focusing on the most important implications for breast surgeons.

Target Audience

This activity has been designed to meet the educational needs of breast surgeons, surgical oncologists, medical oncologists, oncology nurses, nurse practitioners, nurses, and other clinicians involved in the management of patients with breast cancer.

Educational Objectives

Upon completion of this activity, participants will be able to:
  • Discuss the biologic rationale and rational strategies for harnessing the immune system in the treatment of triple-negative breast cancer (TNBC), including combinatorial or sequential approaches with immune checkpoint inhibitors and other effective therapies that may enhance immunogenicity and improve outcomes
  • Assess the efficacy, safety, biomarker, and other key data from clinical trials assessing immunotherapy and immune-based combinations or sequential strategies with other effective treatment modalities throughout the continuum of TNBC, including early-stage (neoadjuvant/adjuvant settings) and advanced/metastatic disease
  • Incorporate immunotherapies into treatment plans for patients with TNBC based on the latest evidence, indications, recommendations, disease stage/treatment setting, patient and tumor characteristics, and other relevant factors in the context of effective multidisciplinary collaboration

Providership, Credit, and Support


This CME/MOC/CNE activity is jointly provided by Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education.

This activity is supported by an educational grant from Merck & Co., Inc.

Physician Continuing Medical Education

ACCMEThis activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education. The Medical Learning Institute, Inc. is accredited by the ACCME to provide continuing medical education for physicians.

The Medical Learning Institute, Inc. designates this enduring material for a maximum of 1.25 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

MOC Statement

MOCSuccessful completion of this CME activity, which includes participation in the evaluation component, enables the participant to earn up to 1.25 MOC points and patient safety MOC Credit in the American Board of Internal Medicine’s (ABIM) Maintenance of Certification (MOC) program. Participants will earn MOC points equivalent to the amount of CME credits claimed for the activity. It is the CME activity provider’s responsibility to submit participant completion information to ACCME for the purpose of granting ABIM MOC credit.

Participation information will be shared with ABIM through the ACCME’s Program and Activity Reporting System (PARS). Blinded individual or aggregated participant data may be shared with the funder of the activity.

Continuing Nursing Education

ANCCMedical Learning Institute, Inc. is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.
Successful completion of this continuing nursing education activity will be awarded 1.25 contact hour(s).

Faculty Disclosures

Chair
George Plitas, MD
Associate Attending, Breast Service, Department of Surgery
Jeanne A. Petrek Junior Faculty Chair
Assistant Professor of Surgery, Weill Cornell Medical College
Memorial Sloan Kettering Cancer Center
New York, New York

George Plitas, MD, has a financial interest/relationship or affiliation in the form of:
Consultant and/or Advisor for Merck & Co., Inc. and Tizona Therapeutics.

Faculty
Alice Y. Ho, MD, MBA
Faculty Member, Department of Radiation Oncology
Massachusetts General Hospital
Associate Professor, Harvard Medical School
Boston, Massachusetts

Alice Y. Ho, MD, MBA, has a financial interest/relationship or affiliation in the form of:
Consultant and/or Advisor for Seattle Genetics, Inc.
Grant/Research Support from Breast Cancer Research Foundation; GlaxoSmithKline; Merck & Co., Inc.; and Translational Breast Cancer Research Consortium.

Heather L. McArthur, MD, MPH
Medical Director, Breast Oncology
Hematology/Oncology
Samuel Oschin Comprehensive Cancer Institute
Cedars-Sinai Medical Center
Los Angeles, California

Heather L. McArthur, MD, MPH, has a financial interest/relationship or affiliation in the form of:
Consultant and/or Advisor for AstraZeneca; Bristol Myers Squibb; Daiichi Sankyo, Inc.; Genentech, Inc; Immunomedics; Merck & Co., Inc.; Pfizer Inc.; Puma Biotechnology, Inc.; and Seattle Genetics.
Grant/Research Support from AstraZeneca; Bristol Myers Squibb; BTG International Ltd.; MedImmune; and Merck & Co., Inc. Research support to Institution.

Planning Committee Disclosures

Tracy L. Greene, MSN, RN, FNP-C, Nurse Planner, MLI, has nothing to disclose.

The planners from Medical Learning Institute, Inc., the accredited provider, and PeerView Institute for Medical Education, the joint provider, do not have any financial relationships with an ACCME-defined commercial interest related to the content of this accredited activity during the past 12 months unless listed below.

Content/Peer Reviewer Disclosures

The following Content/Peer Reviewers have nothing to disclose:

Shaina Rozell, MD, MPH
Bobbie Perrin, FNP-C, OCN, APRN

Disclosure of Unlabeled Use

This educational activity may contain discussions of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Method of Participation

There are no fees for participating in or receiving credit for this accredited activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and will be emailed to you upon completion. You will receive your certificate from email@email.peerviewpress.com. If you have questions regarding the receipt of your emailed certificate, please contact via email at info@PeerView.com.

In order to receive credit, participants must view the activity and complete the post-test and evaluation form. A score of 70% or higher is needed to obtain MOC/CNE credit. There are no prerequisites and there is no fee to participate in this activity or to receive MOC/CNE credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form.

About This CME/MOC/CNE Activity

PVI, PeerView Institute for Medical Education, and Medical Learning Institute, Inc. are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of PeerView activities is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of PVI and Medical Learning Institute, Inc.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerView or any of its partners, providers, and/or supporters.

Copyright © 2000-2020, PeerView

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