Course Director

Giancarlo Castaman, MD
Giancarlo Castaman, MD

Center for Bleeding Disorders and Coagulation
Careggi University Hospital
Florence, Italy


Augusto B. Federici
Augusto B. Federici, MD

University of Milan
Luigi Sacco University Hospital
Milan, Italy

Rezan Abdul Kadir
Rezan Abdul Kadir, MB ChB, MRCOG, FRCS(Ed), MD

University College London School of Medicine
Royal Free Hospital
London, United Kingdom

Accredited by

Oakstone Publishing, LLC

View Activity Materials

Activity Details

Credit Types:CME
Credit Amount:0.5 Credits
Release Date:2018-May-01
Expiration Date:2019-Apr-30
Estimated Time for Completion:30 minutes
Registration Required:No
Cost:Free of Charge

Funding Disclosure

This activity is supported by an educational grant from Shire International GmbH.

Activity Description and Educational Objectives

In this activity, experts in the management of von Willebrand disease (VWD) discuss the limitations of current VWD treatments, as well as considerations in making treatment choices in the haematology and obstetrics/gynaecology settings in order to improve outcomes for this sometimes-challenging group of patients.

Upon completion of this activity, participants should be better able to:

  • Describe the limitations associated with current treatment options for patients with von Willebrand disease (VWD)
  • Summarise clinical strategies to address current VWD treatment limitations
  • Formulate individualised VWD treatment plans for patients who cannot take desmopressin, based on patient- and drug-related characteristics

Target Audience

This activity has been designed to meet the educational needs of haematologists, obstetrician/gynaecologists and other clinicians involved in the management of patients with von Willebrand disease.

Faculty Disclosure Statement / Conflict of Interest Policy

Oakstone Publishing, LLC has assessed conflict of interest with its faculty, authors, editors, and any individuals who were in a position to control the content of this CME activity. Any identified relevant conflicts of interest were resolved for fair balance and scientific objectivity of studies utilized in this activity. Oakstone Publishing’s planners, medical reviewers, and editorial staff disclose no relevant financial relationships with commercial interests.

Course Director and Moderator

Giancarlo Castaman, MD
Director, Center for Bleeding Disorders and Coagulation
Careggi University Hospital
Florence, Italy

Giancarlo Castaman, MD, has a financial interest/relationship or affiliation in the form of:
Consultant for F. Hoffmann-La Roche Ltd.
Grant/Research Support from CSL Behring and Pfizer Inc.
Speaker’s Bureau participant with F. Hoffmann-La Roche Ltd and Shire Plc.
Advisory Board for Bayer AG; CSL Behring; F. Hoffmann-La Roche Ltd; Kedrion S.p.A.; Novo Nordisk Ltd; Sabi Pharma; and uniQure N.V.


Augusto B. Federici, MD
Associate Professor of Hematology
University of Milan
Head of Hematology and Transfusion Medicine
Luigi Sacco University Hospital
Milan, Italy

Augusto B. Federici, MD, has no financial interests/relationships or affiliations in relation to this activity.

Rezan Abdul Kadir, MB ChB, MRCOG, FRCS(Ed), MD
Honorary Reader, University College London School of Medicine
Consultant Obstetrician and Gynaecologist, Royal Free Hospital
London, United Kingdom

Rezan Abdul Kadir, MB ChB, MRCOG, FRCS(Ed), MD, has no financial interests/relationships or affiliations in relation to this activity.

PeerVoice Medical Director

Christy Rohani, PhD

Christy Rohani, PhD, has no financial interests/relationships or affiliations in relation to this activity.

Disclosure of Unlabelled Use

The faculty of this educational activity may include discussions of products or devices that are not currently labelled for use in certain jurisdictions. Faculty members have been advised to disclose to the audience any reference to an unlabelled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses in our materials. No responsibility is taken for errors or omissions in our materials.

Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Oakstone Publishing, LLC and PeerVoice. Oakstone Publishing, LLC is accredited by the ACCME to provide continuing medical education for physicians.

Oakstone Publishing, LLC designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The European Union of Medical Specialists (UEMS)-European Accreditation Council for Continuing Medical Education (EACCME) has an agreement of mutual recognition of continuing medical education (CME) credit with the American Medical Association (AMA). European physicians interested in converting AMA PRA Category 1 Credit™ into European CME credit (ECMEC) should contact the UEMS (

This CME activity is jointly provided by Oakstone Publishing, LLC and PeerVoice.

Requirements for Successful Completion

To receive credit, participants must complete the activity, the post-test, and the evaluation form prior to the expiration date noted below. There are no pre-requisites and there is no fee to participate in this activity or to receive credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form. Consult your professional licensing board for information about your eligibility to claim credit for participation in this educational activity. A minimum performance level of 70% is needed.

Media: Enduring Material
Release and Expiration Dates: May 01, 2018 - April 30, 2019
Time to Complete: 30 minutes


The participants of this educational activity have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerVoice or any of its supporters.

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