Activity Details

Free CME
0.75 AMA PRA Category 1 Credits
Released: August 30, 2018
Expires: August 29, 2019
45 minutes to complete

Jointly Provided By

This activity is jointly provided by Postgraduate Institute for Medicine and RMEI Medical Education, LLC.



Target Audience

Clinicians involved in the care of patients with rheumatoid arthritis (RA).

Learning Objectives

  • Describe involvement of the IL-6 signaling pathway in the pathophysiology, extra-articular symptomology, and associated comorbidities of rheumatoid arthritis (RA), and the role of cytokine-targeted therapy in the treatment of RA
  • Incorporate validated and guideline-recommended RA disease activity monitoring to guide appropriate management of patients
  • Use a treat-to-target approach for managing RA that personalizes therapy by cycling or switching treatment options in nonresponsive patients, and takes into account data for new and emerging biologic and targeted synthetic DMARDs
  • Develop individualized RA treatment strategies that incorporate patient preferences, shared decision making, and patient education



Paul Emery, MA, MD, FRCP, FMedSci (Chair)
Arthritis Research UK Professor of Rheumatology
Leeds Institute of Rheumatic & Musculoskeletal Medicine, University of Leeds
Director, Leeds Biomedical Research Centre
Leeds Teaching Hospitals NHS Trust
Leeds, England (UK)

Jonathan Kay, MD
Professor of Medicine
Timothy S. and Elaine L. Peterson Chair in Rheumatology
Director of Clinical Research, Division of Rheumatology
University of Massachusetts Medical School
Worcester, Massachusetts (USA)

Josef S. Smolen, MD
Professor of Medicine
Chairman, Division of Medicine and Department of Medicine 3
Medical University of Vienna
Vienna, Austria (Europe)

Disclosure of Conflicts of Interest

Postgraduate Institute for Medicine (PIM) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest (COI) they may have as related to the content of this activity. All identified COI are thoroughly vetted and resolved according to PIM policy. PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.

The faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:

  • Paul Emery, MA, MD, FRCP, FMedSci, has affiliations with AbbVie, BMS, MSD, Pfizer, and Roche (Contracted Research/Grants); AbbVie, BMS, MSD, Novartis, Pfizer, Roche, and UCB (Consulting Fees); and AbbVie, BMS, MSD, Novartis, Roche, and UCB (Speakers' Bureau).
  • Jonathan Kay, MD, has affiliations with Eli Lilly and Company, Gilead, Pfizer, and UCB (Contracted Research/Grants); and Amgen, Boehringer Ingelhelm GmbH, Celgene, Celltrion Healthcare, Janssen, Merck Sharpe & Dohme, Myriad Genetics, Pfizer, Roche, Samsung Bioepis, and Sandoz (Consulting Fees).¬†
  • Josef S. Smolen, MD, has affiliations with AbbVie, Astra-Zeneca, Eli Lilly and Company, Janssen, MSD, Pfizer, and Roche (Contracted Research/Grants); and AbbVie, Amgen, Astra-Zeneca, Astro, BMS, Celgene, Celltrion, Chugai, Gilead, Glaxo, Eli Lilly and Company, ILTOO, Janssen, Medimmune, MSD, Novartis-Sandoz, Pfizer, Roche, Samsung, Sanofi, and UCB (Consulting Fees).

Planners and Managers
The PIM planners and managers have nothing to disclose. RMEI Medical Education, LLC planners and managers have nothing to disclose.

Joint Accreditation Statement

In support of improving patient care, this activity has been planned and implemented by the Postgraduate Institute for Medicine and RMEI Medical Education, LLC. Postgraduate Institute for Medicine is jointly accredited by the Accreditation Council for Continuing Medical Education (ACCME), the Accreditation Council for Pharmacy Education (ACPE), and the American Nurses Credentialing Center (ANCC) to provide continuing education for the healthcare team.

The Postgraduate Institute for Medicine designates this enduring material for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

How to Receive Credit

By reviewing the course content and successfully completing the post-test and evaluation, physicians, nurse practitioners, and PAs are entitled to receive up to 0.75 AMA PRA Category 1 Credit(s)™. A statement of credit will be available to print from your user history page. Users must:

  • Read the learning objectives and faculty disclosures.
  • Participate in the activity.
  • Complete the activity evaluation.

Physicians, nurse practitioners, and PAs who successfully complete the post-test and evaluation will receive CME credit. You must score 75% or higher on the post-test to receive credit for this activity. All other participants who successfully complete the post-test and evaluation will receive a certificate of participation. If you would like to contact Postgraduate Institute for Medicine, please email


Complete the Evaluation form for this activity and be entered into a drawing for a $100* Amazon Gift card.
*The expense for this gift card is solely funded by RMEI Medical Education, LLC. No supporter funding was used for the expense of this gift card.

Rules and Regulations 
This sweepstakes is managed by RMEI Medical Education, LLC (RMEI), a full-service medical education company. The winner will be selected via automated random drawing on a monthly basis from among all eligible entries and notified through the contact information provided. In accordance with our privacy policy, we do not share your information with any third parties. By entering the sweepstakes, you grant RMEI permission to use your email address to reach you for notification and prize fulfillment. Only individuals who complete the evaluation forms and provide contact information will be eligible to win. Open to those who have a US postal address and who are 18 years or older. Only one prize per person and per household will be awarded. The prize will be a $100 Amazon gift card.

Statement of Commercial Support

The activity is supported by an educational grant from Sanofi Genzyme and Regeneron Pharmaceuticals.


Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.

Disclosure of Unlabeled Use

This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications.

The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

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