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Activity Details

Free CME/CNE
0.75 AMA PRA Category 1 Credit(s)
0.75 Contact Hour(s)
Released: December 16, 2019
Expires: December 16, 2020
45 minutes to complete

Accredited By

 

Target Audience

Medical oncologists, community oncologists, nurse practitioners, and physician assistants. Other healthcare professionals including radiation oncologists, primary care physicians, pharmacists, and nurses who treat patients with HR+, HER2- metastatic breast cancer (mBC) may also benefit from participation in the educational activity. 

Learning Objectives

Upon completion of this activity, participants should be able to:
  • Evaluate and apply emerging clinical data and evolving strategies for the treatment of metastatic breast cancer to optimize the outcomes of individual patients.
  • Analyze patient and disease characteristics that influence treatment selection for patients with HR+, HER2- metastatic breast cancer.

Activity Description

The treatment landscape for HR+, HER2- metastatic breast cancer has gone through a paradigm shift in treatment, with the advent of targeted therapies. From emerging clinical data to treatment selection, a multidisciplinary panel led by Hope Rugo, MD, FASCO, team up with Vandana Abramson, MD, Erika Hamilton, MD, and Lauren Czapla, NP, to provide a practical update for practicing clinicians on key treatment advances, and analyzing patient and disease characteristics influencing treatment selection for patients with HR+, HER2- metastatic breast cancer.

Statement of Educational Need

With the recent approvals, and new clinical data, medical oncologists, nurse practitioners, and physician assistants are faced with three challenges:
  • Staying abreast of the rapidly expanding evidence base to inform treatment of HR+, HER2- metastatic breast cancer (knowledge-based gaps).
  • Interpreting emerging data of approved and investigational therapies to best guide clinical decision making (competency-based gaps).
  • Analyzing patient and disease characteristics that inform treatment selection for a patient with HR+, HER2- metastatic breast cancer.

Agenda

  • Overview of HR+, HER2- emerging targeted therapies.
  • Tumor–board-style discussion of a patient with HR+, HER2- metastatic breast cancer.
  • Visual guide for treatment selection (algorithm) for HR +, HER2- metastatic breast cancer.

Faculty

Hope S. Rugo, MD, FASCO
Professor of Medicine,
Director, Breast Oncology and Clinical Trials Education
Helen Diller Family Comprehensive Cancer Center
University of California, San Francisco
San Francisco, California


Vandana G. Abramson, MD, MTR
Associate Professor of Medicine,
Division of Hematology-Oncology
Vanderbilt University Medical Center
Nashville, Tennessee


Erika P. Hamilton, MD
Director, Breast and Gynecologic Cancer Program
Sarah Cannon Research Institute/Tennessee Oncology
Nashville, Tennessee


Lauren E. Czapla, RN, MS, WHNP-BC, AOCNP
Nurse Practitioner,
Breast Oncology
Oncofertility Program
Dana-Farber Cancer Institute
Boston, Massachusetts


Conflict of Interest Policy/Disclosure Statement

Disclosure Statement
Educational activities provided by Forefront Collaborative must demonstrate balance, independence, and scientific rigor. All those in a position to control the content of an activity must disclose all relevant financial relationship(s) with commercial interest(s). The disclosures will be listed in the activity handout.

Disclosure and Conflict of Interest Resolution
Educational activities provided by Forefront Collaborative must demonstrate balance, independence, and scientific rigor. All those in a position to control the content of an activity must disclose all relevant financial relationship(s) with commercial interest(s)*. For this educational activity, all conflicts of interest have been resolved through peer review and revisions to ensure independence, evidence base, fair balance, and absence of commercial bias. Disclosures appear below.

*The ACCME defines a commercial interest as any entity producing, marketing, reselling, or distributing health care goods or services consumed by or used on patients. The ACCME does not consider providers of clinical service directly to patients to be commercial interests – unless the provider of clinical service is owned, or controlled by, an ACCME-defined commercial interest.

The following individuals have indicated that neither they nor their spouses/partners have had, in the past 12 months, financial relationship(s) with commercial interests relative to the content of this CME activity:
  • Planners (Forefront Collaborative):
    Megan Ragan
  • Faculty:
    Lauren E. Czapla, RN, MS, WHNP-BC, AOCNP
The following individuals have disclosed that they and/or their spouse/partner has had a financial relationship in the past 12 months:
  • Faculty:
    Hope S. Rugo, MD, FASCO
    Contracted research—Pfizer, Merck, Novartis, Lilly, Genentech, OBI, Odonate, Daiichi-Sankyo, Eisai, Seattle Genetics, MacroGenics, and Immunomedics (all funding to UC Regents)
    Travel support to academic meetings—Daiichi-Sankyo, Mylan, Pfizer, Amgen, Merck, AstraZeneca, MacroGenics, and Puma

    Erika P. Hamilton, MD
    Consultant—Pfizer (institutional compensation, not personal), Cascadian Therapeutics, and Lilly (institutional compensation only, not personal)
    Speakers bureau—Genentech/Roche (institutional compensation only, not personal)
    Advisory board—Lilly (institutional compensation only, not personal)
    Contracted research—Lilly, Pfizer, Genentech/Roche, Hutchison MediPharma, OncoMed, MedImmune, Stemcentrx, AbbVie, Curis, Verastem, Zymeworks, Syndax, Lycra, Rgenix, Novartis, Mersana, TapImmune, BerGenBio, Tesaro, Medivation, Kadmon, Boehringer Ingelheim, Eisai, H3 Biomedicine, Radius Health, Acerta, Takeda, MacroGenics, Immunomedics, Fujifilm, Effector, Syros, Unum, Sutro, Aravive, Deciphera, Clovis, and Sermonix

    Vandana G. Abramson, MD, MTR
    Advisory board—Novartis
    Contracted research—Novartis and Genentech

  • Planners (Forefront Collaborative):
    Wambui Gathirua-Mwangi’s spouse receives a salary from Lilly for work as a research scientist in dermatology.

Accreditation Statement

Forefront Collaborative is accredited by the Accreditation Council for Continuing Medical Education (ACCME) to provide continuing medical education for physicians.

IPMA holds accreditation with commendation from the Accreditation Council for Continuing Medical Education (ACCME) and is approved by the American Board of Medical Specialties as a Multispecialty Portfolio Provider.

Credit Designation Statement

Forefront Collaborative designates this activity for a maximum of 0.75 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

AANP

NP: This activity is approved for 0.75 contact hour(s) of continuing education by the American Association of Nurse Practitioners. Activity ID 19103993. This activity was planned in accordance with AANP Accreditation Standards and Policies.

RN: IPMA is approved by the California Board of Registered Nursing, Provider Number 6971, for 0.75 contact hours. Each person should retain this certificate for 4 years after the course has been completed. RNs outside of California must verify with their licensing agency for approval of this course.

Instructions for Receiving Credit

Participants must complete and submit the online CME/CNE evaluation form at the conclusion of the activity and achieve a passing score of 100%. Certificates will be generated upon completion and submission of the evaluation form.

Statement of Commercial Support

This activity is supported by an educational grant from Lilly. For further information concerning Lilly grant funding, visit www.lillygrantoffice.com.

Disclaimer Statement/Disclosure of Unlabeled Use

The views and opinions expressed in this activity are those of the faculty and do not necessarily reflect the views or recommendations of Forefront Collaborative, Interstate Postgraduate Medical Association, and Lilly.

The content of this activity was independently peer reviewed by two reviewers. The reviewers of this activity have no relevant financial relationships to disclose.

This continuing medical education activity will include reference(s) to unlabeled or unapproved uses of drugs or devices.

Contact Information for Questions About the Activity

Megan_Ragan@forefrontcollab.com
317.601.4742

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