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Course Director

Jame Abraham
Jame Abraham, MD

Director
Breast Oncology Program
Taussig Cancer Institute
Co-Director
Cleveland Clinic Multidisciplinary Breast Cancer Program
Cleveland Clinic, Cleveland, OH

Faculty

G. Thomas Budd, MD

Department of Hematology/Medical Oncology
Taussig Cancer Institute
Cleveland Clinic
Professor of Medicine
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Cleveland Clinic
Cleveland, OH

Maura N. Dickler

Breast Cancer Medicine Service
Memorial Sloan-Kettering Cancer Center
New York, New York, USA

Richard S. Finn
Richard S. Finn, MD

Geffen School of Medicine at UCLA
Los Angeles, California, USA

Gabriel N. Hortobagyi

Department of Molecular and Cellular Oncology
The University of Texas, M.D. Anderson Cancer Center
Houston, Texas, USA

Accredited by

Cleveland Clinic Center for Continuing Education

View Activity Materials

Course Description

Learning Objectives
1. Identify the current standard of care for endocrine therapy in patients with hormone receptor-positive advanced breast cancer
2. Discuss key results of clinical trials of fulvestrant, alone and in combination regimens, for treatment of HR-positive disease
3. State the mechanism of action of CDK4/6 inhibitors and rationale for their use in HR-positive advanced breast cancer
4. Assess the efficacy and safety of CDK4/6 inhibitors observed in recent clinical trials in women with HR-positive, HER2-negative breast cancer and its potential to overcome endocrine resistance
5. Explain the rationale for use of mTOR inhibitors for treatment of patients with HR-positive advanced breast cancer, and summarize recent clinical trial data supporting the efficacy of such agents in this patient population
6. Review biomarker driven decision making in adjuvant and extended adjuvant setting

Activity Details

Credit Types:CME
Credit Amount:1.25 Credits
Release Date:2017-Aug-23
Expiration Date:2019-Aug-23
Estimated Time for Completion:1 hour 15 minutes
Registration Required:No
Cost:Free

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