Jeffrey S. Weber, MD, PhD
Deputy Director
Laura and Isaac Perlmutter Cancer Center
Professor of Medicine
NYU Langone Medical Center
New York, NY

Disclosure: Receipt of Intellectual Property/Patent: Moffitt Cancer Center
Consulting Fee: AstraZeneca, Biodesix, Bristol-Myers Squibb, EMD-Serono, Genentech, GlaxoSmithKline, Medivation, MedImmune, Merck, Nektar, Novartis
Ownership Interest: Alto Biosciences, Celidex, CytoMx

Patricia A. Brock, MD
Deputy Chair
Assistant Professor, Emergency Medicine
University of Texas MD Anderson Cancer Center
Houston, TX

Disclosure: No relevant financial relationships to disclose.

Rajni Kannan, BS, MS, RN, ANP-BC
Nurse Practitioner
Laura and Isaac Perlmutter Cancer Center
NYU Langone Medical Center
New York, NY

Disclosure: Speakers Bureau: Bristol-Myers Squibb

Kathleen M. Madden, MSN, FNP-BC, AOCNP, APHN
Nurse Practitioner
Laura and Isaac Perlmutter Cancer Center
NYU Langone Medical Center
New York, NY

Disclosure: Speakers Bureau: Bristol-Myers Squibb, Merck

Barbara A. Niedz, PhD, RN, CPHQ
Disclosure: No relevant financial relationships to disclose.

Ronald A. Codario, MD, FACP, FNLA, RPVI, CHCP
Disclosure: No relevant financial relationships to disclose.

Vindico Medical Education Staff:
Disclosure: No relevant financial relationships to disclose.

Signed Disclosures are on file at Vindico Medical Education, Office of Medical Affairs and Compliance.

Accredited By

This continuing education activity is provided by

Activity Details


1.0 AMA PRA Category 1 Credit

1.0 Learner-Paced Contact Hour

Released: March 23, 2017

Expires: March 23, 2018

1 hour to complete

No registration required

Activity Description

The incorporation of immunotherapies, especially the immune checkpoint inhibitors, into treatment regimens for patients with cancer, have significantly improved clinical outcomes in these patient populations. The utilization of immune checkpoint inhibitors in cancer therapy are associated with unique immune-related adverse events (irAEs), most commonly manifesting in the skin, gastrointestinal tract, and endocrine system. Patients presenting with immune-related adverse events require prompt diagnosis and treatment to avoid the occurrence of potential life-threatening complications. Therefore, it is imperative that emergency medicine providers are familiar with best practices for diagnosis and management of irAEs. In this activity, a multidisciplinary expert panel provides discussion, evaluation, and guidance for the effective diagnosis, treatment, and management of irAEs in patients with cancer.

Learning Objectives

Upon successful completion of this activity, participants should be better able to:

  • Review the impact of immunotherapy on outcomes for patients with cancer.
  • Differentiate immune-related adverse events (irAEs) from those of traditional treatment modalities.
  • Describe best practices for the identification and management of irAEs.
  • Examine the importance of an interprofessional care team, including the patient/caregiver, in the identification and management of irAEs.

Target Audience

The intended audience for this activity is emergency medicine physicians, oncologists, emergency medicine nurses, oncology nurses, and other health care professionals involved in the treatment of patients with irAEs.

Conflict of Interest Policy / Disclosure Statement

In accordance with the Accreditation Council for Continuing Medical Education’s Standards for Commercial Support, all CME providers are required to disclose to the activity audience the relevant financial relationships of the planners, teachers, and authors involved in the development of CME content. An individual has a relevant financial relationship if he or she has a financial relationship in any amount occurring in the last 12 months with a commercial interest whose products or services are discussed in the CME activity content over which the individual has control. Relationship information appears above.

Accreditation Statement

Vindico Medical Education is accredited by the Accreditation Council for Continuing Medical Education to provide continuing medical education for physicians.

Vindico Medical Education, LLC is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center's Commission on Accreditation.

Designation of Credit

Vindico Medical Education designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Vindico Medical Education will provide 1.0 contact hours for nurses.

Instructions for Receiving Credit

To participate in this CME/CNE activity, you must read the objectives, answer the pretest questions, view the CME/CNE content, and complete the posttest and evaluation. Provide only one (1) correct answer for each question. A satisfactory score is defined as answering 70% of the posttest questions correctly. Upon receipt of the completed materials, if a satisfactory score on the posttest is achieved, Vindico Medical Education will issue an AMA PRA Category 1 Credit(s)™ Certificate or Learner-Paced Contact Hours Certificate.

Statement of Commercial Support

This activity is supported by an educational grant from Bristol-Myers Squibb.

There is no non-commercial support for this activity.

Education activities are distinguished as separate from endorsement of commercial products. When commercial products are displayed, participants will be advised that accredited status as a provider refers only to its continuing education activities and does not imply ANCC Commission on Accreditation endorsement of any commercial products.

Disclaimer Statement / Disclosure of Unlabeled Use

The material presented at or in any Vindico Medical Education continuing education activity does not necessarily reflect the views and opinions of Vindico Medical Education. Neither Vindico Medical Education, nor the faculty endorse or recommend any techniques, commercial products, or manufacturers. The faculty/authors may discuss the use of materials and/or products that have not yet been approved by the US Food and Drug Administration. All readers and continuing education participants should verify all information before treating patients or utilizing any product.

Contact Information for Questions About the Activity

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