Elad Anter, MD

Harvard-Thorndike Electrophysiology Institute
Cardiovascular Division, Department of Medicine
Beth Israel Deaconess Medical Center
Harvard Medical School, Boston, MA

Andre G. Kleber, MD

Markus Rottmann, PhD

Eran Leshem, MD, MHA

Michael Barkagan, MD

Cory M. Tschabrunn, PhD

Fernando M. Contreras-Valdes, MD

Alfred E. Buxton, MD

Accredited by

American College of Cardiology

Course Description

In order to better understand the electrophysiologic substrate underlying ventricular tachycardia (VT) we evaluated electrograms recorded during sinus rhythm at isthmus sites during VT. We found that the tachycardia isthmus corresponds to locations characterized by abnormal conduction properties, with a steep activation gradient (SAG) during sinus rhythm. In particular, the VT critical-zones exhibit SAG during sinus rhythm and consistently occur in areas with voltage amplitude ≤0.55mV. These areas serve as "anchors" for multiple VT configurations and cycle lengths. By contrast, low voltage alone or late potentials are not specific for the isthmus including common anchor sites.

Activity Details

Credit Types:CME
Credit Amount:1.00 Credits
Release Date:2018-Aug-20
Expiration Date:2019-Aug-19
Registration Required:No

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