feedback

Faculty

Jolie Krooks, BS

Charles E. Schmidt College of Medicine,
Florida Atlantic University, Boca Raton, Florida

Milen Minkov, MD, PhD

Department of Pediatrics, Neonatology,
and Adolescent Medicine, Rudolfstiftung Hospital,
Teaching Hospital of the Medical University of Vienna,
Vienna, Austria

Angela G. Weatherall, MD

ClearlyDerm Center for Dermatology,
Department of Clinical Biomedical Science,
Florida Atlantic University, Boca Raton, Florida

Accredited by

American Academy of Dermatology

Course Description

Langerhans cell histiocytosis (LCH) is an inflammatory neoplasia of myeloid precursor cells driven by mutations in the mitogen-activated protein kinase pathway. When disease involves the skin, LCH most commonly presents as a seborrheic dermatitis or eczematous eruption on the scalp and trunk. Evaluation for involvement of other organ systems is essential, because 9 of 10 patients presenting with cutaneous disease also have multisystem involvement. Clinical manifestations range from isolated disease with spontaneous resolution to life-threatening multisystem disease. Prognosis depends on involvement of risk organs (liver, spleen, and bone marrow) at diagnosis, particularly on presence of organ dysfunction, and response to initial therapy. Systemic treatment incorporating steroids and cytostatic drugs for at least one year has improved prognosis of multisystem LCH and represents the current standard of care.

Activity Details

Credit Types:CME
Credit Amount:1.00 Credits
Release Date:2018-Jun-01
Expiration Date:2021-Jun-01
Estimated Time for Completion:1 hour
Registration Required:Yes
Cost:$35.95

Suggest a CME Activity

Please provide below the URL and description of an activity you would like to add to OpenCME. You are welcome to add activities as often as you like. To prevent spam or other abuse, activities are reviewed by our editorial team before appearing on OpenCME.

OpenCME for Publishers

Please use the form below if you would like to offer your website visitors high-quality CME content by adding the OpenCME Widget to one or more of your pages.

Send Email to a Colleague

To share this activity with one or more colleagues, enter their e-mail addresses below. To include a personal message, simply overwrite the suggested text below.

(So your recipient knows it's from you.)
Enter multiple recipients separated by a space.
Optionally, replace/modify in the box above the message that will be sent to your colleague(s) with a link to download this app.