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Accredited by

American Medical Association

Course Description

Importance: The non–vitamin K antagonist oral anticoagulants (NOACs) apixaban, dabigatran, edoxaban, and rivaroxaban are administered in fixed doses without anticoagulant monitoring. Randomized trials show that unmonitored NOAC therapy is at least as effective as and safer than dose-adjusted warfarin for stroke prevention in patients with nonvalvular atrial fibrillation. Subgroup analyses indicate that plasma drug levels or anticoagulant activity of the NOACs predict stroke and bleeding. This review examines the historical basis for anticoagulant monitoring, discusses methods to measure and interpret drug levels, and critically assesses the role of routine laboratory monitoring in the management of NOAC therapy.

Activity Details

Credit Types:CME
Credit Amount:1.00 Credits
Release Date:2017-May-17
Expiration Date:2020-May-17
Estimated Time for Completion:1 hour
Registration Required:Yes
Cost:$30.00

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