Lynette Sholl
Lynette Sholl, MD

Clinical Pathologist
Brigham and Women's Hospital

Apar K. Ganti
Apar K. Ganti, MD

Medical Oncologist
University of Nebraska

Accredited by

American Society of Clinical Oncology

Course Description

This free case-based activity includes a crowd-sourced discussion of a A 70-year-old male non-smoker was in his normal state of health until approximately 2 months ago when he developed progressively worsening low back pain. A lumbar spine MRI displayed multiple lesions and a biopsy of the lumbar spine confirmed adenocarcinoma, most likely, lung primary. Immunostaining showed that the tumor was diffusely positive for keratins (AE1/3, K903, and CK7), TTF-1 and napsin, and negative for CK20, PSA, PAP, CDX-2, CD10, ERG, and CD45. He was started on crizotinib and showed a partial response.

Learning Objectives

- Identify the issues associated with molecular testing for non-small cell lung cancer
- Discuss the optimal management of ALK positive lung cancer
- Describe the mechanisms of resistance to ALK inhibitors

Activity Details

Credit Types:CME / MOC / CNE / CPE
Credit Amount:1.00 Credits
Expiration Date:2020-Apr-25
Registration Required:Yes

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