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Course Director

Leonard Calabrese
Leonard Calabrese, DO

Department of Rheumatic & Immunologic Diseases
Cleveland Clinic
Cleveland, OH

Faculty

R. John Looney, MD

Professor of Medicine
Department of Allergy, Immunology, & Rheumatology
University of Rochester Medical Center
Rochester, NY

Accredited by

Cleveland Clinic Center for Continuing Education

View Activity Materials

Course Description

Learning Objectives
1. List the characteristic effector cytokines produced by each of the 5 major CD4 T cell subsets.
2. Describe the infections resulting from defects in TH1 or TH17, or Tfh cells.
3. Describe the effect of TH2 cells overactivity on infections.
4. Describe the role of TH17 cells in the induction of osteoclasts and the bone erosions associated with inflammatory arthritis. And, describe the effects of TH1 and TH2 cells on the induction of osteoclasts by TH17 cells.
5. Describe non-classical TH1 cells (also know as ex-TH17 cells) and how the multiple cytokine produced by these cells complicate treatment.
6. Describe tissue resident T cells and how they are involved in the Koebner phenomenon.

Activity Details

Credit Types:CME
Credit Amount:0.50 Credits
Release Date:2020-Apr-08
Expiration Date:2022-Apr-08
Estimated Time for Completion:30 minutes
Registration Required:No
Cost:Free

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