Course Director

Matthew D. Hellmann, MD
Matthew D. Hellmann, MD

Memorial Sloan Kettering Cancer Center
New York, New York

Accredited by

Medical Learning Institute, Inc.

Activity Details

Credit Types:CME
Credit Amount:0.5 Credits
Release Date:2018-May-29
Expiration Date:2019-May-28
Estimated Time for Completion:30 minutes
Registration Required:No
Cost:Free of Charge

Activity Description and Educational Objectives

In this activity, an expert in immuno-oncology will explore the present and future of cancer immunotherapy biomarkers, as well as practical considerations for biomarker testing across the oncologic spectrum.

Upon completion of this activity, participants should be better able to:

  • Characterize the evolving cancer immunotherapy landscape, including agents/combinations and current and emerging indications for their use
  • Discuss the current role and benefits/limitations of PD-L1 expression testing as a predictive biomarker for cancer immunotherapies
  • Describe the options and nuances of MMR/MSI status testing to predict benefit from cancer immunotherapies
  • Assess the emerging role of TMB as an immunotherapy biomarker, and benefits/limitations of different methodologies and platforms, including NGS, for assessing TMB
  • Interpret the results of cancer immunotherapy biomarker testing to guide clinical decisions regarding optimal use of cancer immunotherapies across the hemato-oncologic spectrum

Target Audience

This activity has been designed to meet the educational needs of medical oncologists, pathologists, and other healthcare professionals interested in immuno-oncology, immunotherapy biomarkers, and precision oncology.

Requirements for Successful Completion

In order to receive credit, participants must view the activity and complete the post-test and evaluation form. A score of 70% or higher is needed to obtain CME credit. There are no pre-requisites and there is no fee to participate in this activity or to receive CME credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form.

Media: Enduring Material
Release and Expiration Dates: May 29, 2018 - May 28, 2019
Time to Complete: 30 minutes

Faculty and Disclosure / Conflict of Interest Policy

Before the activity, all faculty and anyone who is in a position to have control over the content of this activity and their spouse/life partner will disclose the existence of any financial interest and/or relationship(s) they might have with any commercial interest producing healthcare goods/services to be discussed during their presentation(s): honoraria, expenses, grants, consulting roles, speakers bureau membership, stock ownership, or other special relationships. Presenters will inform participants of any off-label discussions. All identified conflicts of interest are thoroughly vetted by Medical Learning Institute, Inc. for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The associates of Medical Learning Institute, Inc., the accredited provider for this activity, and PVI, PeerView Institute for Medical Education do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this CME activity during the past 12 months.

Course Director

Matthew D. Hellmann, MD
Medical Oncologist
Memorial Sloan Kettering Cancer Center
New York, New York

Matthew D. Hellmann, MD, has a financial interest/relationship or affiliation in the form of:
Consultant for AstraZeneca; Bristol-Myers Squibb; Genentech, Inc./F. Hoffmann-La Roche Ltd; Janssen Pharmaceuticals, Inc.; Merck & Co., Inc.; Mirati Therapeutics, Inc.; Shattuck Labs; and Syndax Pharmaceuticals Inc.
Grant/Research Support from Bristol-Myers Squibb.

Matthew D. Hellmann, MD, does intend to discuss either non-FDA-approved or investigational use for the following products/devices: immuno-oncology biomarkers and testing platforms; immune checkpoint inhibitors and combinations.

CME Reviewer

Vishwanath Sathyanarayanan, MD, DM
Apollo Hospitals
Bangalore, Karnataka, India

Vishwanath Sathyanarayanan, MD, DM, has no financial interests/relationships or affiliations in relation to this activity.

Medical Director

Kadrin Wilfong, MD
PVI, PeerView Institute for Medical Education

Kadrin Wilfong, MD, has no financial interests/relationships or affiliations in relation to this activity.


The information provided at this CME activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient's medical condition. Recommendations for the use of particular therapeutic agents are based on the best available scientific evidence and current clinical guidelines. No bias towards or promotion for any agent discussed in this program should be inferred.

Providership, Credit, and Support

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education. The Medical Learning Institute, Inc. is accredited by the ACCME to provide continuing medical education for physicians.

The Medical Learning Institute, Inc. designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


This CME activity is jointly provided by Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education.


This activity is supported through an educational grant from Bristol-Myers Squibb.

Disclosure of Unlabeled Use

The faculty of this educational activity may include discussions of products or devices that are not currently labeled for use by the FDA. Faculty members have been advised to disclose to the audience any reference to an unlabeled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses in our reports. No responsibility is taken for errors or omissions in reports. For approved prescribing information, please consult the manufacturer’s product labeling.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerView or any of its partners, providers, and/or supporters.

About This CME Activity

PVI, PeerView Institute for Medical Education, and Medical Learning Institute, Inc. are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of PeerView activities is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of PVI and Medical Learning Institute, Inc.

Copyright © 2000-2018, PeerView

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