Course Director

Isabel Conceicao, MD
Isabel Conceicao, MD

Universidade de Lisboa
CHLN Hospital Santa Maria
Lisbon, Portugal


Marianna Fontana
Marianna Fontana, MD, PhD

University College London
National Amyloidosis Center
London, UK

Ole B. Suhr
Ole B. Suhr, MD

Umeå University
Umeå, Sweden

Accredited by

Oakstone Publishing, LLC

View Activity Materials

Activity Details

Credit Types:CME
Credit Amount:0.5 Credits
Release Date:2018-Nov-30
Expiration Date:2019-Nov-29
Estimated Time for Completion:30 minutes
Registration Required:No
Cost:Free of Charge

Funding Disclosure

This activity is supported by an educational grant from Alnylam Switzerland GmbH.

Activity Description and Educational Objectives

In this activity, experts in the management of transthyretin amyloidosis (ATTR) discuss the latest approaches and tools that may help with diagnosis, and the current and emerging treatment options that could reduce neurologic impairment and improve quality of life for patients with this disease.

Upon completion of this activity, participants should be better able to:
  • Apply evidence-based and guideline-recommended strategies to improve diagnosis of patients with transthyretin amyloidosis (ATTR)
  • Describe the clinical evidence evaluating current and emerging treatment strategies for ATTR
  • Evaluate the role of current and emerging treatment strategies as part of a multidisciplinary approach to managing patients with ATTR

Target Audience

This activity has been designed to meet the educational needs of neurologists, cardiologists, and other clinicians involved in the management of transthyretin amyloidosis.

Faculty Disclosure Statement / Conflict of Interest Policy

Oakstone Publishing, LLC has assessed conflict of interest with its faculty, authors, editors, and any individuals who were in a position to control the content of this CME activity. Any identified relevant conflicts of interest were resolved for fair balance and scientific objectivity of studies utilized in this activity. Oakstone Publishing’s planners, medical reviewers, and editorial staff disclose no relevant financial relationships with commercial interests.

Course Director and Moderator

Isabel Conceição, MD
Faculty of Medicine, Universidade de Lisboa
Consultant in Neurology and Neurophysiology
Department of Neurosciences
CHLN Hospital Santa Maria
Lisbon, Portugal

Isabel Conceição, MD, has a financial interest/relationship or affiliation in the form of:
Consultant for Alnylam Pharmaceuticals Inc.; Pfizer Inc.; and Sanofi SpA.
Grant/Research Support from Pfizer Inc.
Honoraria from Alnylam Pharmaceuticals Inc.; Pfizer Inc.; and Sanofi SpA.
Advisory Board for Alnylam Pharmaceuticals Inc.; Pfizer Inc.; and Sanofi SpA.


Marianna Fontana, MD, PhD
Senior Lecturer, University College London
Honorary Consultant Cardiologist
National Amyloidosis Center
London, United Kingdom

Marianna Fontana, MD, PhD, has a financial interest/relationship or affiliation in the form of:
Consultant for Alnylam Pharmaceuticals Inc. and GlaxoSmithKline Plc.

Ole B. Suhr, MD
Professor, Department of Public Health and Clinical Medicine
Umeå University
Umeå, Sweden

Ole B. Suhr, MD, has a financial interest/relationship or affiliation in the form of:
Consultant for Akcea Therapeutics and Alnylam Pharmaceuticals, Inc.
Speaker’s Bureau participant with Alnylam Pharmaceuticals, Inc. and Pfizer Inc.
Advisory Board for Akcea Therapeutics; Alnylam Pharmaceuticals, Inc.; and Prothena Corporation plc.

PeerVoice Medical Director

Stuart Crayford has no financial interests/relationships or affiliations in relation to this activity.

Disclosure of Unlabelled Use

The faculty of this educational activity may include discussions of products or devices that are not currently labelled for use in certain jurisdictions. Faculty members have been advised to disclose to the audience any reference to an unlabelled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses in our materials. No responsibility is taken for errors or omissions in our materials.

Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Oakstone Publishing, LLC and PeerVoice. Oakstone Publishing, LLC is accredited by the ACCME to provide continuing medical education for physicians.

Oakstone Publishing, LLC designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

The European Union of Medical Specialists (UEMS)-European Accreditation Council for Continuing Medical Education (EACCME) has an agreement of mutual recognition of continuing medical education (CME) credit with the American Medical Association (AMA). European physicians interested in converting AMA PRA Category 1 Credit™ into European CME credit (ECMEC) should contact the UEMS (

This CME activity is jointly provided by Oakstone Publishing, LLC and PeerVoice.

Requirements for Successful Completion

To receive credit, participants must complete the activity, the post-test, and the evaluation form prior to the expiration date noted below. There are no pre-requisites and there is no fee to participate in this activity or to receive credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form. Consult your professional licensing board for information about your eligibility to claim credit for participation in this educational activity. A minimum performance level of 70% is needed.

Media: Enduring Material
Release and Expiration Dates: November 30, 2018 - November 29, 2019
Time to Complete: 30 minutes


The participants of this educational activity have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patients' conditions and possible contraindications on dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerVoice or any of its supporters.

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