New Insights and Considerations for Antiplatelet Therapies in Acute Coronary Syndromes: Making it Work for Your Practice Enduring Archive Webcast
Faculty
Deepak L. Bhatt, MD, MPH, FACC, FAHA, FSCAI
Activity Chair
Chief of Cardiology, VA Boston Healthcare System
Director, Integrated Interventional Cardiovascular Program
Brigham and Women's Hospital and VA Boston Healthcare System
Senior Investigator, TIMI Study Group
Associate Professor of Medicine, Harvard Medical School
Boston, Massachusetts
Christopher P. Cannon, MD
Activity Chair
Senior Investigator, TIMI Study Group
Cardiovascular Division, Brigham and Women’s Hospital
Professor of Medicine, Harvard Medical School
Boston, Massachusetts
Accredited by

The Postgraduate Institute for Medicine
Activity Details
| Release Date: |
January 16, 2012 |
| Expiration Date: |
January 16, 2013 |
| Credit Types: |
CME/CE |
| Credit Amount: |
Physician: 1.0 AMA PRA Category 1 Credit(s)™
Pharmacist: 1.0 contact hour(s) (0.1 CEUs)
Nurse: 1.0 contact hours.
|
| Estimated Time for Completion: |
60 minutes |
| Registration Required: | No |
| Cost: | Free |
information@pimed.com
www.pimed.com
Overview
Antiplatelet therapies are the cornerstone of treatment for patients with acute coronary syndrome (ACS) or those undergoing percutaneous coronary intervention (PCI). However, despite many advances in antiplatelet treatments, ACS-related incidence, morbidity, and mortality remain significant. This risk may be due to several barriers, including a lack of optimal dosing information, response variability, potential drug-drug interactions, poor adherence to guideline-recommended therapy, and insufficient utilization of cardiac rehabilitation. With the rapid emergence of data in this field, there are urgent educational needs to highlight the latest developments in order to keep clinicians updated, and more importantly, how to integrate new data into clinical practice.
To achieve this goal, this activity will begin with an overview of the current state of antiplatelet therapy. A case will be used to highlight the current guidelines regarding antiplatelet and adjuvant therapies; the role of genetic testing and platelet function testing in determining antiplatelet response variability; current understanding regarding the appropriate dosage and duration of antiplatelet therapies; potential drug-drug interactions; the importance of balancing antithrombotic efficacy with bleeding risk; and how to identify patients in which more potent therapy may be beneficial and those in which it is contraindicated. This information will be summarized into practical strategies so the participants can implement guideline-recommended therapies in their practices.
Learning Objectives
At the conclusion of this activity, participants should be better able to:
- Select an individualized antiplatelet regimen in patients with ACS based on efficacy and safety data from clinical trials
- Consider factors influencing the choice of antiplatelet therapy, such as ischemic and bleeding risk, genetic testing and platelet function testing, response variability, and drug-drug interaction
- Implement a guideline-recommended antiplatelet therapy in patients with ACS
- Provide accurate and appropriate care and counsel for patients and their families as part of the treatment plan for ACS
Target Audience
This activity is designed for cardiologists, registered nurses, pharmacists, and other healthcare professionals who are interested in the management of patients with ACS.
Agenda
| 10 minutes |
Overview |
| 40 minutes |
Case of Patient with Myocardial Infarction:
Guideline Recommendations for Management |
| 10 minutes |
Question and Answer Session |
Physician Continuing Medical Education
Accreditation Statement
This activity has been planned and implemented in accordance with the Essential Areas and policies of the Accreditation Council for Continuing Medical Education through the joint sponsorship of the Postgraduate Institute for Medicine and ACCELMED. The Postgraduate Institute for Medicine is accredited by the ACCME to provide continuing medical education for physicians.
Credit Designation
The Postgraduate Institute for Medicine designates this enduring material for a maximum of 1.0
AMA PRA Category 1 Credit(s)™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.
Pharmacy Continuing Education
Accreditation Statement
The Postgraduate Institute for Medicine is accredited by the Accreditation Council for Pharmacy Education as a provider of continuing pharmacy education.
Credit Designation
The Postgraduate Institute for Medicine designates this continuing education activity for 1.0 contact hour(s) (0.1 CEUs) of the Accreditation Council for Pharmacy Education. (Universal Activity Number – 0809-9999-12-022-H01-P)
Live ACPE date: 9/13/2011
If you have participated in the live activity, UAN 0809-9999-11-080-L01-P, you are not eligible to claim credit for this activity.
Nursing Continuing Education
This educational activity for 1.0 contact hours is provided by the Postgraduate Institute for Medicine.
Accreditation Statements

The Postgraduate Institute for Medicine is accredited as a provider of continuing nursing education by the American Nurses Credentialing Center’s Commission on Accreditation.
Provider approved by the California Board of Registered Nursing, Provider Number 13485, for 1.0 contact hours.
Disclosure of Conflicts of Interest
The Postgraduate Institute for Medicine (PIM) assesses conflict of interest with its instructors, planners, managers and other individuals who are in a position to control the content of CME activities. All relevant conflicts of interest that are identified are thoroughly vetted by the PIM for fair balance, scientific objectivity of studies utilized in this activity, and patient care recommendations. The PIM is committed to providing its learners with high quality CME activities and related materials that promote improvements or quality in healthcare and not a specific proprietary business interest of a commercial interest.
The
faculty reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:
| Name of Faculty or Presenter |
Reported Financial Relationship |
| Deepak L. Bhatt, MD, MPH, FACC, FAHA, FSCAI, FESC |
Contracted Research: AstraZeneca; Bristol-Myers Squibb Company; Eisai Inc.; sanofi-aventis; The Medicines Company |
| Christopher P. Cannon, MD |
Contracted Research: Accumetrics, Inc.; AstraZeneca; GlaxoSmithKline; Intekrin Therapeutics, Inc.; Merck & Co., Inc.; Takeda Pharmaceuticals North America, Inc.
Advisory Boards: (funds donated to charity): Alnylam Pharmaceuticals, Bristol-Myers Squibb Company/sanofi-aventis Partnership; Novartis International AG
Clinical Advisor, Equity: Automedics Medical Systems
|
The
planners and
managers reported the following financial relationships or relationships to products or devices they or their spouse/life partner have with commercial interests related to the content of this CME activity:
The following PIM planners and managers, Jan Hixon, RN, BSN, MA, Trace Hutchison, PharmD, Julia Kimball, RN, BSN, Samantha Mattiucci, PharmD, Jan Schultz, RN, MSN, CCMEP, and Patricia Staples, MSN, NP-C, CCRN hereby state that they or their spouse/life partner do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this activity of any amount during the past 12 months.
The following ACCELMED planner and manager, Janardhan Sampath, PhD, hereby states that his spouse/life partner is an employee of Lilly USA, LLC.
Disclosure of Unlabeled Use
This educational activity may contain discussion of published and/or investigational uses of agents that are not indicated by the FDA. The Postgraduate Institute for Medicine (PIM), ACCELMED, Daiichi Sankyo, Inc. and Lilly USA, LLC do not recommend the use of any agent outside of the labeled indications.
The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the PIM, ACCELMED, Daiichi Sankyo, Inc. and Lilly USA, LLC. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.
Disclaimer
Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient’s conditions and possible contraindications on dangers in use, review of any applicable manufacturer’s product information, and comparison with recommendations of other authorities.
Type of Activity
Knowledge
Fee Information
There are no fees for participating and receiving CME credit for this activity. During the period January 16, 2012 through January 16, 2013, participants must read the learning objectives and faculty disclosures and study the educational activity.
PIM supports Green CME by offering your Request for Credit online. If you wish to receive acknowledgment for completing this activity, please complete the post-test and evaluation on
www.cmeuniversity.com. On the navigation menu, click on “Find Post-test/Evaluation by Course” and search by project ID 8097. Upon registering and successfully completing the post-test with a score of 70% or better and the activity evaluation, your certificate will be made available immediately. Processing credit requests online will reduce the amount of paper used by nearly 100,000 sheets per year.
Hardware / Software Requirements
Flash Player 6.0.79 or later (
http://www.adobe.com/go/getflash) (Flash Player 7 or later recommended), and one of the following browsers:
Windows: Internet Explorer 6, Internet Explorer 7, Firefox 1.x and later, Safari 3, Google Chrome, Opera 9.5
Macintosh: Firefox 1.x and later, Safari 3
Linux: Firefox 1.x

Jointly sponsored/co-provided by Postgraduate Institute for Medicine and ACCELMED

This activity is supported by an educational grant from Daiichi Sankyo, Inc. and Lilly USA, LLC.