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Course Director

David Miklos, MD, PhD
David Miklos, MD, PhD

Stanford University
Stanford, California

Faculty

John F. DiPersio
John F. DiPersio, MD, PhD

Washington University School of Medicine
St. Louis, Missouri

Accredited by

The Medical College of Wisconsin

Activity Details

Credit Types:CME
Credit Amount:1.0 Credits
Release Date:2018-Apr-11
Expiration Date:2019-Apr-10
Estimated Time for Completion:60 minutes
Registration Required:No
Cost:Free of Charge

Activity Description and Educational Objectives

In this activity, based on a recent live symposium at the 2018 BMT Tandem Meetings, experts in hematology-oncology and bone marrow transplantations take a deep dive into the underlying immunology of graft-versus-host disease (GVHD) and the latest evidence with approved and emerging classes of innovative therapeutics, as well as provide expert insight on the practical application of these advancements as prophylaxis or for treatment of acute and chronic, steroid-nonresponsive, and previously untreated GVHD.

Upon completion of this activity, participants should be better able to:
  • Describe the underlying immunology of post-transplant GVHD, and the rationale for and mechanisms of novel therapies in the management of GVHD
  • Summarize efficacy and safety evidence on novel therapeutic options, such as JAK1/2 inhibitors and BTK inhibitors, for GVHD prophylaxis and treatment in HSCT recipients
  • Recommend ongoing clinical trials assessing new strategies and combinations of agents to eligible patients with acute or chronic, steroid-naïve or steroid-refractory GVHD in the HSCT setting

Target Audience

This activity has been designed to meet the educational needs of hematologist-oncologists, oncologists, BMT specialists, BMT nurse specialists, and other clinicians involved in the management of patients with GVHD.

Requirements for Successful Completion

In order to receive credit, participants must view the activity and complete the post-test and evaluation form. There are no pre-requisites and there is no fee to participate in this activity or to receive CME credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form.

Media: Enduring Material
Release and Expiration Dates: April 11, 2018 - April 10, 2019
Time to Complete: 60 minutes

Faculty and Disclosure / Conflict of Interest Policy

In accordance with ACCME requirements, The Medical College of Wisconsin has a conflict of interest policy that requires faculty to disclose relevant financial relationships related to the content of their presentations/materials. Any potential conflicts are resolved so that presentations are evidence-based and scientifically balanced.

Course Director and Moderator

David Miklos, MD, PhD
Associate Professor of Medicine
Clinical Director, Cancer Cell Therapy Program
Stanford University, Division of Blood and Marrow Transplantation
Stanford, California

David Miklos, MD, PhD, has a financial interest/relationship or affiliation in the form of:
Grant/Research Support from Adaptive Biotechnologies; Kite Pharma; and Pharmacyclics LLC.
Other Financial or Material Support from Scientific Advisory Board for Adaptive Biotechnologies; Kite Pharma; Novartis Pharmaceuticals Corporation; Pfizer Inc.; and Pharmacyclics LLC.

Faculty

John F. DiPersio, MD, PhD
Virginia E. and Samuel J. Golman Professor in Medicine
Chief, Division of Oncology
Deputy Director, Alvin J. Siteman Cancer Center
Professor of Medicine, Pathology & Immunology
Washington University School of Medicine
St. Louis, Missouri

John F. DiPersio, MD, PhD, has a financial interest/relationship or affiliation in the form of:
Consultant for Amphivena Therapeutics, Inc.; Asterias Biotherapeutics; BioLineRx; Bristol-Myers Squibb Company; Cellworks Group Inc.; Rivervest; and Vasculox, Inc.
Speakers Bureau participant with Dava Oncology.
Stock Shareholder in Magenta Therapeutics (Founder).
Advisory Board for Amphivena Therapeutics, Inc.; Asterias Biotherapeutics; BioLineRx; Bristol-Myers Squibb Company; Cellworks Group Inc.; Rivervest; and Vasculox, Inc.
Other Financial or Material Support from Grant Review for Hemedicus.

Medical Director

Aarati Ranganathan, PhD
PVI, PeerView Institute for Medical Education

Aarati Ranganathan, PhD, has no financial interests/relationships or affiliations in relation to this activity.

The Medical College of Wisconsin (MCW) requires instructors, planners, managers, and other individuals who are in a position to control the content of this activity to disclose any real or apparent conflict of interest they may have as related to the content of this activity. All identified conflicts of interest are thoroughly vetted by MCW for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

Providership, Credit, and Support

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of The Medical College of Wisconsin and PVI, PeerView Institute for Medical Education. The Medical College of Wisconsin is accredited by the ACCME to provide continuing medical education for physicians.

The Medical College of Wisconsin designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Hours of Participation for Allied Health Care Professionals:

The Medical College of Wisconsin designates this activity for up to 1.0 hours of participation for continuing education for allied health professionals.

Providership

This CME activity is jointly provided by The Medical College of Wisconsin and PVI, PeerView Institute for Medical Education.

Support

This activity is supported by educational grants from Incyte Corporation and Pharmacyclics LLC, an AbbVie Company, and Janssen Biotech, Inc., administered by Janssen Scientific Affairs, LLC.

Disclosure of Unlabeled Use

The faculty of this educational activity may include discussions of products or devices that are not currently labeled for use by the FDA. Faculty members have been advised to disclose to the audience any reference to an unlabeled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses in our reports. No responsibility is taken for errors or omissions in reports. For approved prescribing information, please consult the manufacturer’s product labeling.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerView or any of its partners, providers, and/or supporters.

About This CME Activity

PVI, PeerView Institute for Medical Education, and The Medical College of Wisconsin are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of PeerView activities is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of PVI and The Medical College of Wisconsin.

Copyright © 2000-2018, PeerView

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