Course Director

Leonard Calabrese
Leonard Calabrese, DO

Department of Rheumatic & Immunologic Diseases
Cleveland Clinic
Cleveland, OH


R. John Looney, MD

Professor of Medicine
Department of Allergy, Immunology, & Rheumatology
University of Rochester Medical Center
Rochester, NY

Accredited by

Cleveland Clinic Center for Continuing Education

View Activity Materials

Course Description

Learning Objectives
1. Describe the major subsets of CD4+ effector T cells and the role of cytokines in generation of these cells.
2. Explain the role of signal 1, signal 2, and signal 3 in the activation of naive T cells.
3. Discuss the important cytokines produced by TH1, TH2, and TH17 cells.
4. Describe the role of TH1 and TH2 cells in hypersensitivity reactions and allergy and how the balance between TH1 and TH2 cells affects the outcome of infections.
5. Describe the role of TH1, TH2, and TH17 cells in host defenses and how defects in these cells lead to immunodeficiencies.

Activity Details

Credit Types:CME
Credit Amount:1.00 Credits
Release Date:2017-Mar-14
Expiration Date:2019-Mar-14
Estimated Time for Completion:1 hour
Registration Required:No

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