Course Director

Leonard Calabrese
Leonard Calabrese, DO

Department of Rheumatic & Immunologic Diseases
Cleveland Clinic
Cleveland, OH


R. John Looney, MD

Professor of Medicine
Department of Allergy, Immunology, & Rheumatology
University of Rochester Medical Center
Rochester, NY

Accredited by

Cleveland Clinic Center for Continuing Education

View Activity Materials

Course Description

Learning Objectives
1. Describe the 2 steps involved in secretion of IL1β.
2. Describe the components of an inflammasome and how inflammasome activation provides the second step in activation of IL1β.
3. List diseases where IL1β blockade is remarkably effective.
4. Describe the effect of IL1β inhibition by canakinumab in the Cantos study on cardiovascular events and lung cancer.
5. Discuss the diagnosis and treatment of Schnitzler’s syndrome

Activity Details

Credit Types:CME
Credit Amount:0.25 Credits
Release Date:2020-Apr-08
Expiration Date:2022-Apr-08
Estimated Time for Completion:15 minutes
Registration Required:No

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