Course Director

Mark T. Reding, MD
Mark T. Reding, MD

University of Minnesota Medical Center
Minneapolis, Minnesota

Accredited by

Medical Learning Institute, Inc.

View Activity Materials

Activity Details

Credit Types: CME / CE
Credit Amount: 0.5 CME / 1.0 CE
Release Date: 2018-Feb-21
Expiration Date: 2019-Feb-20
Estimated Time for Completion: 30 minutes
Registration Required: No
Cost: Free of charge

Activity Description and Educational Objectives

In this activity, a hematology expert discusses extended half-life replacement clotting factors and coagulation assay and reagent selection in patients with hemophilia A.

Upon completion of this activity, participants will be able to:
  • Describe how recombinant replacement clotting factors have been modified in order to extend their half-life in patients with hemophilia
  • Apply recent data on approved and emerging extended half-life replacement clotting factors for the management of hemophilia A
  • Identify current techniques for assaying pharmacokinetic and pharmacodynamic parameters in patients with hemophilia A
  • Select the appropriate assay for monitoring pharmacokinetic and pharmacodynamic parameters in individuals with hemophilia A based on the extended half-life replacement clotting factor being utilized for prophylaxis

Target Audience

This activity has been designed to meet the educational needs of coagulation laboratory directors and technicians, hematologists, hemophilia specialists, hematology nurses, and other clinicians involved in the management of patients with hemophilia.

Nursing Education Purpose Statement

The purpose of this activity is to improve knowledge and competence of nurses concerning the treatment of hemophilia.

Requirements for Successful Completion

In order to receive credit, participants must view the activity and complete the post-test and evaluation form. A score of 70% or higher is needed to obtain CME/CE credit. There are no pre-requisites and there is no fee to participate in this activity or to receive CME/CE credit. Statements of Credit are awarded upon successful completion of the post-test and evaluation form.

Media: Enduring Material
Release and Expiration Dates: February 21, 2018 - February 20, 2019
Time to Complete: 30 minutes

Faculty & Disclosure / Conflict of Interest Policy

Before the activity, all faculty and anyone who is in a position to have control over the content of this activity and their spouse/life partner will disclose the existence of any financial interest and/or relationship(s) they might have with any commercial interest producing healthcare goods/services to be discussed during their presentation(s): honoraria, expenses, grants, consulting roles, speakers bureau membership, stock ownership, or other special relationships. Presenters will inform participants of any off-label discussions. All identified conflicts of interest are thoroughly vetted by Medical Learning Institute, Inc. for fair balance, scientific objectivity of studies mentioned in the materials or used as the basis for content, and appropriateness of patient care recommendations.

The associates of Medical Learning Institute, Inc., the accredited provider for this activity, and PVI, PeerView Institute for Medical Education do not have any financial relationships or relationships to products or devices with any commercial interest related to the content of this CME/CE activity during the past 12 months.

Course Director

Mark T. Reding, MD
Associate Professor of Medicine
Director, Center for Bleeding and Clotting Disorders
University of Minnesota Medical Center
Minneapolis, Minnesota

Mark T. Reding, MD, has a financial interest/relationship or affiliation in the form of:
Speakers Bureau participant with Bioverativ and Shire.
Advisory Board for Bayer Corporation; Bioverativ; Genentech, Inc.; Novo Nordisk A/S; Pfizer Inc.; and Shire.
Mark T. Reding, MD, does intend to discuss either non-FDA-approved or investigational use for the following products/devices: extended half-life clotting factors for hemophilia A management.

CME Reviewer

Amer Assal, MD
Columbia University Medical Center
Blood and Marrow Transplantation Program
New York, New York

Amer Assal, MD, has no financial interests/relationships or affiliations in relation to this activity.

Nurse Reviewer

Pamela Ash, RN, MSN, CBCN
Mary Babb Randolph Cancer Center Clinic
West Virginia University
Morgantown, West Virginia

Pamela Ash, RN, MSN, CBCN, has no financial interests/relationships or affiliations in relation to this activity.

Medical Director

Kirk A. Tacka, PhD
PVI, PeerView Institute for Medical Education

Kirk A. Tacka, PhD, has no financial interests/relationships or affiliations in relation to this activity.


The information provided at this CME/CE activity is for continuing education purposes only and is not meant to substitute for the independent medical judgment of a healthcare provider relative to diagnostic and treatment options of a specific patient’s medical condition. Recommendations for the use of particular therapeutic agents are based on the best available scientific evidence and current clinical guidelines. No bias towards or promotion for any agent discussed in this program should be inferred.

Providership, Credit & Support


This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education. The Medical Learning Institute, Inc. is accredited by the ACCME to provide continuing medical education for physicians.

The Medical Learning Institute, Inc. designates this enduring material for a maximum of 0.5 AMA PRA Category 1 Credits™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.


Medical Learning Institute, Inc.
Provider approved by the California Board of Registered Nursing, Provider Number 15106, for 1.0 contact hour(s).


This CME/CE activity is jointly provided by Medical Learning Institute, Inc. and PVI, PeerView Institute for Medical Education.


This activity is supported by an educational grant from Bayer HealthCare Pharmaceuticals Inc.

Disclosure of Unlabeled Use

The faculty of this educational activity may include discussions of products or devices that are not currently labeled for use by the FDA. Faculty members have been advised to disclose to the audience any reference to an unlabeled or investigational use.

No endorsement of unapproved products or uses is made or implied by coverage of these products or uses in our reports. No responsibility is taken for errors or omissions in reports. For approved prescribing information, please consult the manufacturer’s product labeling.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerView or any of its partners, providers, and/or supporters.

About This CME/CE Activity

PVI, PeerView Institute for Medical Education, and Medical Learning Institute, Inc. are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of PeerView activities is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of PVI and Medical Learning Institute, Inc.

Copyright © 2000-2018, PeerView

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