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Course Director

Steven Brem, MD
Steven Brem, MD

Penn Brain Tumor Center
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

Faculty

Manmeet Ahluwalia
Manmeet Ahluwalia, MD, FACP

Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic
Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Cleveland, Ohio

Steven A. Toms
Steven A. Toms, MD, MPH, FAANS, FACS

LPG Neurosurgery-Norman Prince Neuroscience Institute
Lifespan Physician Group, Inc.
The Warren Alpert Medical School of Brown University
Providence, Rhode Island

Accredited by

Medical Learning Institute, Inc.

Activity Description

The advent of the fourth treatment modality, tumor treating fields (TTFields), and ongoing research on novel systemic agents are continuing to improve clinical outcomes for patients with glioblastoma. In this activity, based on a recent live symposium planned in collaboration with the American Brain Tumor Association and held during the 24th Annual Meeting of the Society for Neuro-Oncology, neuro-oncology experts discuss cutting-edge advancements with TTFields therapy and the future outlook on novel targeted agents for patients with glioblastoma. Additionally, the faculty share stories about real patients to highlight how scientific advancements and clinical data translate into personalized care.

Target Audience

This activity has been designed to meet the educational needs of neuro-oncologists, neurosurgeons, radiation oncologists, medical oncologists, pathologists, advanced practice clinicians, and other healthcare professionals involved in the care of patients with glioblastoma.

Educational Objectives

Upon completion of this activity, participants should be better able to:
  • Summarize the biologic rationale of TTFields, immunotherapy, multikinase and TRK inhibitors, among other drug classes for the treatment of glioblastoma
  • Assess the latest clinical evidence on currently available treatment strategies, such as TTFields and targeted TRK inhibitors, for newly diagnosed and recurrent glioblastoma
  • Review recent safety and efficacy evidence on novel agents under investigation, including immune checkpoint and multikinase inhibitors, for the therapeutic management of glioblastoma
  • Develop personalized treatment plans for patients with glioblastoma (both newly diagnosed and recurrent), including the consideration of enrolling in clinical trials

Providership, Credit, and Support


This CME activity is jointly provided by Medical Learning Institute, Inc., the American Brain Tumor Association, and PVI, PeerView Institute for Medical Education.

This activity is supported by educational grants from Bayer HealthCare Pharmaceuticals Inc., Karyopharm Therapeutics, Inc., and Novocure.

Physician Continuing Medical Education

This activity has been planned and implemented in accordance with the accreditation requirements and policies of the Accreditation Council for Continuing Medical Education (ACCME) through the joint providership of the Medical Learning Institute, Inc., the American Brain Tumor Association, and PVI, PeerView Institute for Medical Education. The Medical Learning Institute, Inc. is accredited by the ACCME to provide continuing medical education for physicians.

The Medical Learning Institute, Inc. designates this enduring material for a maximum of 1.0 AMA PRA Category 1 Credit™. Physicians should claim only the credit commensurate with the extent of their participation in the activity.

Faculty Disclosures

Chair

Steven Brem, MD
Chief, Neurosurgical Oncology
Co-Director, Penn Brain Tumor Center
Professor of Neurosurgery
Perelman School of Medicine
University of Pennsylvania
Philadelphia, Pennsylvania

Steven Brem, MD, has a financial interest/relationship or affiliation in the form of:
Consultant and/or Advisor for Tocagen.
Data Safety Monitoring Board for Advantagene, Inc.

Faculty

Manmeet Ahluwalia, MD, FACP
Miller Family Endowed Chair in NeuroOncology
Associate Director and Head of Operations
Burkhardt Brain Tumor and Neuro-Oncology Center, Cleveland Clinic
Professor, Cleveland Clinic Lerner College of Medicine of Case Western Reserve University
Cleveland, Ohio

Manmeet Ahluwalia, MD, FACP, has a financial interest/relationship or affiliation in the form of:
Consultant and/or Advisor for AbbVie Inc.; AstraZeneca; Bayer Corporation; Elsevier; Flatiron; Forma Therapeutics; Karyopharm; Tocagen; Varian Medical Systems, Inc.; and VBI Vaccines Inc.
Grant/Research Support from AbbVie Inc.; AstraZeneca; Bayer Corporation; Bristol-Myers Squibb; Incyte Corporation; Merck & Co., Inc.; Novocure; and Pharmacyclics LLC.
Stock Shareholder in Doctible and MimiVax.
Other financial interest/relationship from Wiley in the form of royalties as the book editor.

Steven A. Toms, MD, MPH, FAANS, FACS
Vice Chair, Department of Neurosurgery
Director, Brain Tumor and Stereotactic Radiosurgery Program
LPG Neurosurgery-Norman Prince Neuroscience Institute
Co-Director of the Molecular Neuroscience and Neuro-Oncology
Research Laboratory
Lifespan Physician Group, Inc.
Professor of Neurosurgery, Medicine, and Health Services, Policy and Practice
The Warren Alpert Medical School of Brown University
Providence, Rhode Island

Steven A. Toms, MD, MPH, FAANS, FACS, has no financial interests/relationships or affiliations in relation to this activity.

Planning Committee Disclosures

The planners from Medical Learning Institute, Inc., the accredited provider, PeerView Institute for Medical Education, and the American Brain Tumor Association, joint providers, do not have any financial relationships with an ACCME-defined commercial interest related to the content of this accredited activity during the past 12 months unless listed below.

Content/Peer Reviewer Disclosures

The following Content/Peer Reviewer has nothing to disclose:

Shaina Rozell, MD, MPH

Disclosure of Unlabeled Use

This educational activity may contain discussions of published and/or investigational uses of agents that are not indicated by the FDA. The planners of this activity do not recommend the use of any agent outside of the labeled indications. The opinions expressed in the educational activity are those of the faculty and do not necessarily represent the views of the planners. Please refer to the official prescribing information for each product for discussion of approved indications, contraindications, and warnings.

Disclaimer

Participants have an implied responsibility to use the newly acquired information to enhance patient outcomes and their own professional development. The information presented in this activity is not meant to serve as a guideline for patient management. Any procedures, medications, or other courses of diagnosis or treatment discussed or suggested in this activity should not be used by clinicians without evaluation of their patient's conditions and possible contraindications and/or dangers in use, review of any applicable manufacturer's product information, and comparison with recommendations of other authorities.

Method of Participation

There are no fees for participating in or receiving credit for this accredited activity. For information on applicability and acceptance of continuing education credit for this activity, please consult your professional licensing board.

A statement of credit will be issued only upon receipt of a completed activity evaluation form and will be emailed to you upon completion. You will receive your certificate from email@email.peerviewpress.com. If you have questions regarding the receipt of your emailed certificate, please contact via email at info@peerview.com.

About This CME Activity

PVI, PeerView Institute for Medical Education, and Medical Learning Institute, Inc. are responsible for the selection of this activity’s topics, the preparation of editorial content, and the distribution of this activity. Our activities may contain references to unapproved products or uses of these products in certain jurisdictions. The preparation of PeerView activities is supported by educational grants subject to written agreements that clearly stipulate and enforce the editorial independence of PVI and Medical Learning Institute, Inc.

The materials presented here are used with the permission of the authors and/or other sources. These materials do not necessarily reflect the views of PeerView or any of its partners, providers, and/or supporters.

Copyright © 2000-2019, PeerView

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